How to solve aging

Answers to this question can be found online in the forms of shorter and longer term roadmaps. One could infer an answer from SENS or get a list of ideas from Celine Halioua's recent take on the matter (On what the field needs rather than how to deal with the problem itself). This is just my view. An important question for anyone wanting to answer "How to solve aging" is "If aging is solved, have we then made a given individual, in normal conditions, immortal?" Or "Have we thus made…

Links (47)

Want to own the Longevity FAQ as an NFT? You can bid for it here. Why has nuclear power been a flop? Construction costs around the world: How does the US compare? Coming full circle, from endless complexity to simplicity and back again (On the history of cancer research) What evidence do we need for biomarker qualification (at the FDA)? How was it found that lithium works as a psychiatric drug? Roundtable on Richard Hamming Review of "The Kill Chain" Why is everything liberal (as in leftist)? Beca…

Cozy futurism

Last year I tweeted about something I called cozy futurism; Cool-shit futurism (space colonization, moon telescopes, tech for the sake of tech to some extent) vs cozy futurism (urban reform, renewable energy, solving climate change; focusing on specific problems and having tech as an ends) are categories I've been thinking about recently— José Luis Ricón Fernández de la Puente (@ArtirKel) November 10, 2020 Recently there were a series of tweets that got me thinking again about the same idea; Spac…

Links (46)

A roundtable on Richard Hamming Combination therapies are very rare, but on my view underrated, outside of oncology. A paper on their origin, in the treatment of tuberculosis. Related work. Noah Smith interview with Patrick Collison and explainer on inflation A call for a new World Fair Some social science bashing coming from social scientists Andrew Gelman Private cities in China Fusion startups continue to make progress Spencer Greenberg on self-control The New Space Race, with some cost charts In case yo…

New Models for Funding and Organizing Science

In a previous post in the Fund People, not Projects series I talked about a potential new structure for a hypothetical funding agency. That was just one proposal among many one could make. This post has a set of other such proposals, along with a brief justification for why it might be a good idea. The proposals are not fully fleshed out but they are meant to be inspirational, and intended to be more broadly in the right direction than precisely ready for implementation. The Young Researchers Research Insti…

The levers of NIH: Paths to reform

In my Fund People, Not Projects post series I discussed various reforms that have been proposed to change the way science is funded. NIH is the world's largest science-funding entity (or entities), singlehandedly funding 60% of global non-private life sciences research in 2013. Given the possibilities of the life sciences, it is of interest to understand what one would have to do if one wanted to implement these reforms at NIH. Do you just need to convince the Director of an Institute to get changes approve…