Laura Deming on understanding

Interesting uses of AI

The memes of the wealthy

Elon dreams and bitter lessons

Nabeel on Palantir

Scott reviews Deep Utopia

Meditation, considered harmful

There is no placebo effect

Dwarkesh interviews Gwern

Restoring fertility with iMSC transplantation in monkeys

Profile of James Fickel, a not very well known crypto backer of many impactful projects in the longevity space

The King and the Golem, by Richard Ngo

A recent study in monkeys claimed metformin works to slow down aging. Not so fast, says the SENS foundation

I haven't done a deep dive on seed oils yet but my base take is that they are ok in low quantities - though you shouldn't be using oil other than olive oil (it's the tastiest and healthiest) and you shouldn't be deep frying stuff if you really care about health. Some thoughts from BJ on this. An article from Levels as well with a similar take.

Life in HD: on jhanaing (And anti-jhanaing)

Spicy take(down) of YC and Paul Graham-thought (ht/ Richard Ngo for the link)

CRISPR babies are here to stay, the question is how

Video about Science Corporation

Claude as therapist, various tweets

Pacific Fusion, another fusion company just launched

How many ways are there to build life? Not that many perhaps

Unlocking the emotional brain, a unified theory of therapy

Alzheimer's and inflammation

Otherness and control in the age of AGI

Sheekey Science Show on skin rejuvenation