Target-based drug discovery hasn't worked that well historically.

Metformin, most likely not a longevity drug


Interesting new paper on LLMs being dumb in an weird way: training a model on "A is B" does not necessarily confer the knowedge that "B is A"; another LLMs are less impressive than we thought here.

Scott Alexander comment highlights on his Elon Musk post

Against and For Automaticity

A step towards delivery of gene therapy to the brain: using ultrasound to disrupt the blood brain barrier

Does basting work?

Exowombs are upon us

Nicole Paulk at the All In Summit on gene therapy

How to sabbatical: a tactical guide

Latest Anthropic drop

A song: Revel in Time