Deriving multiple aging clocks out of looking at blood plasma; also includes nice table of proteins that accumulate (or decrease their frequency) with age and what they might be doing.
Bryan Caplan on Matt Yglesias' One Billion Americans
In the same way that the secretome of stem cells can ameliorate Alzheimer in a mouse model(See previous links), stem cells may not be needed to help regenerate injuries to the heart (in this case, in pigs), just what they secrete, as if telling cells "hey there are stem cells around" suffices.
Transcript of a China Talk podcast on Chinese innovation policy
Peter Attia on a recent study that purportedly shows that time restricted feeding (or intermittent fasting) does not work.
"the median student in, say, Senegal scores at about the 2nd percentile in Germany."
Survey of ways to measure cellular senescence
Niskanen Center's comprehensive policy manifesto
Many aging-related studies are on mice, worms, yeast, and flies. Here's a relatively comprehensive review of aging in every other animal model but those, including even bacteria.
In this month's Biology is Wild section, cells are able to throw away defective mitochondria, letting macrophages getting rid of them.
Water fluoridation does seem to work. While a widespread policy, surprisingly the evidence behind it was quite thin, until now.
Paper finds that investors don't discriminate against women per se, but against feminine traits (Regardless of who is expressing them)
Patrick McKenzie on working at Stripe
Most countries (surveyed) think that China, not the US, is the world's dominant power
Whereas ~90% of 40 yearolds identifies as straight, for the younger generations this number is quite lower: 65% straight for women and 85% for men; what is striking is the gap.
Eirini Malliaraki on moonshots
What is Amazon?
A major breakthrough in organ transplantation: using antibodies to precondition the receiver (still mice) of a transplant so that they tolerate it. This is in contrast to the current approach that uses highly destructive whole body irradiation or other nonspecific techniques.
Glucosepane is one of the reasons our bodies (say arteries) get stiffer as we get older, leading to diabetes or eye-related macular degeneration. It is hard to target (it is what people call "undruggable") at the moment. A key step towards that has been achieved with an antibody that binds to glucosepane.
Adam Ashwal on progress in biology
Some evidence that coming up with good ideas works best if this is done individually at first, without having everyone sharing in a group.
A fun paper argues that laws mandating special car seats for children, due to the cost they impose, cause people to have fewer kids, so on net there are less kids being born than kids that are saved, making it a net-negative policy.
Tutoring works, but the effects may be smaller than I pointed to in my original Bloom review, says a new paper
Mark Lutter asks: How could a charter city help biotech?
How to get transistors smaller than 3nm
A new paper on the role of the extra-cellular matrix on cancer (ht/ Eli Dourado)